Thymus activity measured by T-cell receptor excision circles in patients with different severities of respiratory syncytial virus infection
نویسندگان
چکیده
منابع مشابه
Thymus activity measured by T-cell receptor excision circles in patients with different severities of respiratory syncytial virus infection
BACKGROUND Respiratory syncytial virus (RSV) infection is an important cause of hospitalization in previously healthy infants. Immunological mechanisms predisposing infants to severe disease are poorly understood. Early biomarkers for disease severity may assist clinical decisions. We investigated T-cell receptor excision circles (TREC), episomal DNA made during thymic T-cell receptor rearrange...
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In this study we aimed to define the protein and viral subtype specificities of helper Th cells to respiratory syncytial virus (RSV). BALB/c mice were primed by infection with RSV, or with vaccinia viruses (VV) containing genes encoding several individual RSV proteins. Priming for Th cell memory was assayed by stimulating spleen cells in vitro with different RSV isolates and measuring RSV-speci...
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ژورنال
عنوان ژورنال: BMC Infectious Diseases
سال: 2017
ISSN: 1471-2334
DOI: 10.1186/s12879-016-2148-0